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Open Forum
Global Economic Crisis:INDIAN PHARMA industry LETHARGIC, by Radhakrishna Rao,26 December 2008 |
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Events & Issues
New Delhi, 26 December 2008
Global Economic
Crisis
INDIAN PHARMA industry LETHARGIC
By Radhakrishna Rao
Not long back, the buoyant and fast growing Indian pharmaceutical
industry had raised hopes of turning the country into a veritable “pharma power
house” of the world in the not too distant future. Spurred on by a steady
growth in the export of drugs, formulations, vaccines and outsourcing of
various services, the pharma sector was justifiably optimistic of making it to
the world’s top ten by value in the near future. However, the global economic
slow down coupled with a credit crunch prevailing in the Indian market has
conspired to slow down the industry’s prospects.
Accordingly, a spokesman of the Indian pharma industry
admits that “a perceptible slow down in industrial production and economic
growth have been a major causative factor for a decline in our growth
projection.” A forecast by Pharmexcil, a Government of India agency that
monitors the export volume of drugs and pharmaceutical products reveals that
exports are likely to drop by 5 per cent during the current financial year i.e.
these will touch Rs 361-billion as against the original projection of Rs 382-billion.
Incidentally, pharma exports account for 6 per cent of the
total export from India.
However, appreciation of the US green buck against the Rupee has not in any way
gone to benefit the Indian pharma exporters. “The depreciation gains are being
offset as imports have become more expensive now. India
imports its raw materials for manufacturing drugs and pharma products from China and other
countries. But the Rupee depreciation has disabled us” reveals an industry
spokesman.
The US,
which happens to be the world’s largest market for generic drugs accounts for
half of India’s
total pharma and drugs export. However, the ongoing slow down in the American
economy has resulted in a decline in the sale of pharma products and this could
in turn exert a negative impact on the volume of pharma products exported to the
US.
“With the new Obama
Government, we expect sales to drop further. This means that the bottom line of
the Indian companies, which export to the US, will be affected. We expect our
global exports to grow by 14-15 per cent during 2008 in comparison to 20 per
cent last year” observes the head of Pharma Exports Council of India. However, there is a silver lining for the
pharma industry: in recent years, European countries have emerged as a
lucrative alternative market for Indian pharma products and services.
The ongoing global economic melt down has also adversely
affected the expansion plans of the pharma sector. For instance, Reliance
Pharmaceuticals is mulling a scale down of its planned products portfolio from an
initial 75 products to just 25. Earlier, the company had drawn an ambitious and
comprehensive plan for an impressive foray into the regulated US and European markets
with its high value generics. This apart, industry sources are also worried
about a possible decline in “outsourcing”, considered a growth area of the
Indian pharma industry, in this recent financial
crisis.
In the meantime, the Indian pharma companies are hopeful of
making good the projected loss on the export front through increased sales in
the domestic market. The rural hinterland is tipped to be the growth area for
their products. Fortunately, all said and done, the Indian drugs and
pharmaceutical sector looks at the current slow down as a temporary phase and
is quite optimistic of surging ahead with renewed vigour once the crisis blows
over.
This can be said, following a major triumph for the
industry, wherein Hyderabad-based Dr.Reddy’s Laboratory has announced that
Betapharma AG, its wholly-owned subsidiary has been offered eight drug
contracts in different regions of Germany. Says its spokesman: “for
the eight products offered, we expect a significant increase in volume though at
relatively lesser margins”.
Indeed, the global excellence achieved by the Indian pharma
industry, including cases such as Dr Reddy’s and Ranbaxy, and the strides made
by the research organizations and biotech outfits in developing novel drugs and
enzymes are slowly turning India into a major hub for clinical trials of drugs
and vaccines developed by the Western pharma giants.
Thus amidst all this, clinical research is one of the most promising
growth areas for the Indian pharma sector. As a fallout of a steady increase in
outsourcing by western pharma and drug firms, the number of Indian outfits in
the area of clinical research has crossed to 100 from less that 10 a few years ago.
Not surprisingly then, keen on getting a slice of the highly lucrative clinical research
outsourcing market, many pharma and biotech companies in India are busy setting
their house in order and preparing themselves for being world-class clinical
research units.
In fact, by all counts there is a growing realization that
India would need to strengthen its infrastructure for trial sites and enhance
its quality level of clinical trails through ramping up of the operations with
a particular focus on training and evaluation of test procedures. As pointed
out by Dr.Ramananda Nadig, President, Clinical Research Education and
Management Academy (CREMA) “India’s clinical trial industry will require at
least 20,000 investigators and over 30,000 managers by 2010”
A fact-filled status report brought out by global consulting
firm McKinsey reveals that India has the potential to become the third largest market
for pharma products and services in terms of incremental growth, after the US
and China. By 2015, this market is expected to assume a size of US$20-billion.
Moreover, with a rapid and sustained expansion of health
care services, the demand for new and innovative pharma products and novel therapies
is expected to go up by substantial extent. As things stand now, Indian pharma
industry is poised to move up the value chain by making transition from reverse
engineering to discovery and development of new molecules. India has also
emerged as a preferred global supplier of high quality drugs and intermediaries
at an affordable price.
In the ultimate analysis, there is no denying the fact that the
Indian drugs and pharmaceutical sector has made rapid forays into the global
arena, across varying business segments and has clearly shown its ability to
play a leadership role in each of these, notwithstanding the global economic
crisis. –INFA
(Copyright, India News and Feature
Alliance)
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Return of Avian Flu:PREVENTION NOT CURE IS REMEDY, by Radhakrishna Rao, 31 December 2008 |
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People & Their
Problems
New
Delhi, 31 December 2008
Return of Avian Flu
PREVENTION NOT CURE IS REMEDY
By Radhakrishna Rao
The dreaded avian flu has resurfaced
with a vengeance, posing a serious threat to the flourishing poultry industry
in Assam and parts of
adjoining West Bengal. It was in November 2007
that the prevalence of this much-feared viral disease affecting domestic
poultry was first detected in the outskirts of Guwahati. From there, the
disease sneaked into parts of West Bengal, throwing
the over Rs.40, 000-crore poultry sector of the State into turmoil.
It led to some panic selling among
poultry farmers and traders started taking advantage of the situation by
forcing them to sell broilers at un-remunerative prices. In fact, the waves of
fear caused by the spread of disease in Assam
and West Bengal have led to poultry prices dropping
by around 25% across the country. In addition, there is a fear that the spread
of the disease could also affect the export prospects of the poultry industry.
Not surprisingly many countries have
put India
under their “watch list” insofar as buying poultry products are concerned.
However, the biggest relief is that so far no country has officially banned
import of our poultry products. Significantly, the country’s export of poultry
products has increased from Rs.2870-million during 2004-05 to Rs.3500-million
during 2007-08. The major chunk of the revenue for Indian poultry products was from
West Asian countries, Japan
and Germany.
With an annual poultry production of two-million tonnes India is ranked
fifth among the largest poultry producing countries.
More than half a million birds,
including chicken and ducks have already been culled in over seven locations of
Assam
and the local administration has already paid a compensation of Rs.1.45-crore
to the poultry farmers. Meanwhile, in a related development about 60 chicks
seized from the Railway Police in Orissa, while being transported from West
Bengal were culled in Rourkela. This was the
second such culling incident in Orissa after a thousand-odd birds, transported
into the State in a passenger bus were culled near Balasore.
Unfortunately, the bad news of the
avian flu resurfacing in Assam
came in less than three weeks after India was considered free from this
disease, which has the potential to spread to humans. Though still not a global
pandemic, avian flu is known to have killed around 300 people since 2003. Experts
specializing in poultry diseases have pointed out that the H5NI virus, which is
responsible for the avian flu and kills poultry animals also manages to
exchange genetic material between species of specific viruses.
As a matter of fact, the severity of
the disease affecting humans is determined by the state of the immune system. However,
there is no effective cure to treat the disease, the symptoms of which include,
fever, cough, sore throat, muscle pain,
conjunctivitis and in some cases breathing complications and pneumonia.
Oseltamivir, commercially marketed under the brand name Tamiflu helps in
inhibiting the spread of virus, but the World Health Organisation is uncertain about
the drug’s effectiveness.
According to a study by the Food and
Agriculture Organisation (FAO) the H5 NI bird flu virus “has not only become
more contagious to humans but has managed to persist in parts of Asia, Africa
and probably even Europe,” and warns that it has the potential to trigger a
human influenza pandemic.
The People for Ethical Treatment of
Animals (PETA) is of the opinion that the unhygienic conditions in the poultry
farms of Assam was most likely the cause
for the out break of avian flu. Apparently it had warned the Assam Government in
June 2008 about the disease surfacing again but regrettably it wasn’t taken seriously.
The H5NI virus thus affected 120 villages spread across the seven districts of
the State. Like the popular adage, of bolting the stable after the horses have
left, the Assam Government decided to set up an expert committee to hopefully prevent
a similar outbreak of the disease in future. On another front, its Forest
Department has decided to monitor the migratory birds visiting the State during
this winter.
Recall, that the WHO had termed the
outbreak of bird flu in West Bengal in January 2007 as the worst-ever case reported
in India. Over four million birds had then been culled. The reason given was
that the viral strain causing the avian flu spreads with stunning rapidity, and
the best preventive measure was to immediately cull the domesticated birds on a
largescale. It goes without saying that medical researchers are now concerned
that the H5NI virus could acquire genetic strength” to facilitate its spread
from humans to humans in the long run.
A disquieting feature of bird flu is
that there is no fool-proof protection against it through vaccination. This is
so because no one is certain as to what shape the virus would assume after
mutation period. “Viral disease such as avian influenza does not recognize
boundaries. The development of an indigenous vaccine, however, could go a long
way towards tackling its threat effectively” according to the Indian Council of
Agricultural Research.
Apparently, it has been seen that
H5NI virus flourishes and causes fatalities in areas where humans are in close
touch with domesticated birds, such as chickens and fowls. At the same time,
the FAO is of the firm opinion that properly cooked poultry and eggs are safe
to consume. However, as a precautionary measure, partially cooked poultry and
raw eggs need to be avoided. This is so because eggs can carry H5NI virus both
on the outside and the inside.
”People need to be informed about
the importance of basic hygiene, notably washing hands after touching poultry
and disinfecting boots or shores before
entering or leaving a poultry farm” is FAO advice. Even then, oweverk, How there remains the concern that mass
culling of birds could put people at risk of acquiring the virus. And, as only
a small percentage of the population is aware of the dangers of bird flu, it is
time we educate the public and launch an intensified awareness campaign about
the do’s and don’ts. Why wait for another episode? ---INFA
(Copyright, India News and Feature
Alliance)
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The Divine Religion:SWAMI DAYANAND, ARYA SAMAJ & VEDAS, by Dr. Prashanta Kumar Sahoo,28 Nov 08 |
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PEOPLE AND THEIR
PROBLEMS
New Delhi, 28 November 2008
The Divine Religion
SWAMI DAYANAND,
ARYA SAMAJ & VEDAS
By Dr. Prashanta Kumar
Sahoo
A small boy of 14, Mulshankar was asked by his father, Amba
Shankar to keep night vigil on Sivaratri. The heart of this little boy was
filled with eagerness to see god
Siva in a bodily form. He remained awake
all through the night. But to his utter astonishment a rat climbed up the idol
and ate away the offerings.
This trifling incident had a very strong influence on
Mulshankar’s life. It became a turning
point. He became skeptical of idol
worship. He was very thoughtful and
religious by nature. But he could not
satisfy his spiritual thirst with the prevailing religious practices. So he left his home in search of the real
Siva and the real religion.
He wandered among the sadhus
in different parts of India. But he could not find any formula or way to
realize God. Everywhere he saw
hypocrisy, not true religion. He was
deeply disappointed. At last he met
Swami Virajanand who was an ocean
of Sanskrit learning.
Mulshankar became his disciple. Swami Virajanand filled his heart with vast
Vedic knowledge.
The skepticism was gone and Mulshankar developed a staunch
faith in the Vedas and God. Swami
Virajanand convinced his disciple satisfactorily that idolatry was not allowed
in the Vedas and the real Vedic religion was quite different from and much
purer and sublimer than what had passed
for orthodox Hinduism down the ages through the corrupting influence of time.
After the completion of his Vedic studies Mulashankar became
Swami Dayanand and set out to resurrect the divine Vedic religion and preach it
to the mankind. His anti-idolatry preaching evoked unprecedented opposition
from orthodox Hindus. Once even his life was in danger in Varanasi.
But his incessant preaching
all over India
had its effect at last; people began to be convinced that Swami Dayanand’s
interpretation of the Vedas and the Vedic religion was correct and that idoltry
was not permissible in the ancient
religion based on the Vedas, the Arya Dharma.
Swami Dayanand founded the Arya Samaj on April 7, 1875 in Bombay. “Arya Samaj” is a Sanskrit compounded of two
words ‘Arya’ and ‘Samaj’. ‘Arya’ means a righteous man, high-souled, a man possessed of
noble qualities. ‘Samaj’ means a society
or organization. Thus, ‘Arya Samaj’ means a society of persons who mean to be
good and to make others good. Swami Dayanand laid down the following ten
principles of the Arya Samaj:
1) Of all true knowledge and whatever is known from
knowledge, the primary cause is God; 2) God is an embodiment of truth;
intelligence and bliss; and without
form, all-powerful, just, kind, unborn, infinite, unchangeable, beginningless, incomparable, support of all, lord of all, all-pervading,
omniscient, undeteriorable, immortal, fearless,
eternal, holy and Creator of the Universe.
He alone is worthy of worship; 3) the Vedas are the books of all true
knowledge. It is the paramount duty of
all Aryas to read them, to teach them, to hear them and to preach them; 4) we
should be ever ready to accept truth and renounce untruth; 5) everything should
be done according to Dharma, that is, after considering what is truth and what
is untruth;
6) the chief object of the Arya Samaj is to do good to the
world, that is, to make physical, spiritual and social improvement; 7) we
should treat all with love and justice according to their deserts (what they
deserve); 8) we should dispel ignorance and diffuse knowledge; 9) nobody should
remain contended with his personal progress;
one should count the progress of all
as his own and; 10) everyone should consider himself as bound in obeying social
and all benefiting rules, but everyone is free in matters pertaining to
individual well-being.
The four Vedas – the Rig Veda, Yajur Veda, Samaveda and the
Atharva Veda are the basis of the Arya Samaj and Vedic religion. The Arya Samaj
believes that the Vedas are not only the oldest religious books available, but
the oldest, older than humanity and revelationary in character. They were originally revealed by God to the
four rishis Agni, Vayu, Aditya and
Angiras in the beginning of the world and from them they have come down to us
through a chain of innumerable rishis.
The Vedas are an independent authority on points of religion
which derive sanction directly from God. But other scriptures are believable
only so far as they are in consonance with the Vedas.
The following sacred books are accepted by the Arya Samaj as
authoritative: the Brahmana; Aitareya Brahmana;
Satapatha Brahmana; Katha Aitareya, Taittiriya, Prasna, Mundaka, Mandukya
Chhandogya, Brihadaranyaka, and Svetasvatra, and six Angas: Siksa or orthography, Kalpa
or rituals, Vyakarna or grammar, Nirukta or word-study, Chhanda or metres and Jyotis or astronomy. Also accepted by
the Arya Samaj are the six Upangas:
the Nyaya or rhetoric of Gotama, the Sankhya of Kapila, the Vaisesika
or Kanada, the Yoga of Patanjali,
the Purva Mimansa of Jaimini and Uttar Mimansa or Vedanta of Vyasa; Manusmriti or
code of Manu; Griha Sutras or codes
of ceremonials like Paraskara, Gobhil,
Asvalayana and Apastamba; and
last of all Swami Dayanand’s commentaries on the Vedas and other books
including the Satyarthaprakasa.
The Arya Samaj does not accept the authority of the eighteen
Puranas and the Upa-Puranas where the spirit is anti-Vedic. For the Arya Samaj, God is one and the
plurality of governor of the Universe is an absurdity. God also does not
incarnate as coming into flesh implies weakness.
Arya Samaj looks upon God as the great controller of laws which govern the
Universe.
The Arya Samaj branches have been established in a large
number of countries all over the world since 1875. They have been engaged in preaching the
divine Vedic religion to human beings in different parts of the world. Thus,
Swami Dayanand’s effort to resurrect the ancient and pure Vedic religion for
the benefit of mankind has been bearing fruit.---INFA
(Copyright,
India News and Feature Alliance)
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India Over The Moon:ISRO EYES OTHER PLANETS, by Radhakrishna Rao,22 November 2008 |
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SCIENCE SPECIAL
New Delhi, 22 November 2008
India Over The Moon
ISRO EYES OTHER PLANETS
By Radhakrishna Rao
The successful insertion of India’s first lunar probe
Chandrayaan-1 launched on 22 October into the critical lunar orbit after a
series of challenging maneouvers has come as a shot in the arm for the Indian
Space Research Organisation (ISRO).As many lunar probes of leading space-faring
nations including USA and Russia were lost during the process of insertion into
lunar orbit where the gravity of the earth and moon cancels each other.
Against this backdrop, India’s success in the first
attempt testifies to the excellence of our space scientists and technologists
who left nothing to chance while nudging Chandrayaan-1 into lunar orbit. The
Terrain Mapping Camera (TMC) onboard Chandrayaan-1 has already transmitted
beautiful imageries of the earth and the moon.
Buoyed up by the success of Chandrayaan-1 mission, ISRO has
now set its sights on far-off planets the exploration of which not long back
was the exclusive domain of advanced industrialized countries. After the moon,
it is now the sun for ISRO which has unveiled an ambitious plan to launch a
satellite mission designed to probe in depth the dynamics of the solar corona,
the outermost and most active region of the sun.
Named Aditya, the Indian solar mission will study the
dynamics of the solar corona and its impact on atmosphere and ionosphere. This
first Indian solar probe aimed at studying the coronal mass ejection and
associated space weather processes is expected to provide important information
on solar activity conditions.
Capable of observing the corona in both visible and near
infrared bands, Aditya meaning Sun in Sanskrit is planned to be launched well
in time for the next high solar activity period during 2012. The last solar
maximum took place in 1989.
The ISRO has also hinted that it is well equipped to send a
probe to the Red Planet, Mars. The ISRO Chairman G.Madhavan Nair revealed that
inputs for the Mars mission are awaited from the country’s scientific community.
This would help give a specific shape to the proposed I Mars probe. In all
probability, ISRO would go in for an orbiter to explore Mars which is expected
to be the next outpost of the human civilization.
According to S.Ramakrishnan, Projects Director at India’s
largest space establishment, Thiruvananthapuram’s Vikram Sarabhai Space Centre
(VSSC) the Mars probe studies have already started and the three-stage
cryogenic fuel-driven Geosynchronous Satellite Launch Vehicle (GSLV) could
carry a one tone heavy spacecraft to Mars. ISRO has also a well conceived plan
for exploring the inner asteroid belt and comets.
Meanwhile, as a follow up to Chandryaan-1, ISRO has
initiated work on the Chandrayaan-II mission which will be a lander/rover
mission. The Rs.42,000m Chandrayaan-II, which has received the green signal
from the Central Government is planned to be launched during 2011-12. It will be launched by means of a GSLV flight.
However, unlike the Chandrayaan-1 mission, the Chandrayaan-II
probe will be a joint Indo-Russian mission. Russia
will provide the lander/rover and India will build the main
spacecraft. The rover equipped with wheels will land on the lunar surface and
perform the in situ chemical analysis of the collected rock and soil samples. The
data will subsequently be transmitted to the main spacecraft.
Like its predecessor, Chandrayaan-II is expected to
accommodate foreign payloads along with Indian instrumentation systems for
studying various aspects of the moon. “We are looking at having a soft-landing
for Chandrayaan-II instead of a hard landing .We should be working on
technologies that will be part of the proposed moon base. If we were to become
a developed country by 2020, it will be crucial for us to develop such
technologies” asserted M.Annadurai, Project Director of Chandrayaan-1 mission.
Meanwhile, ISRO scientists are looking at the possibility of
going in for a sample return mission to the moon after the completion of the Chandrayaan-II
project. But the proposal is still in an embryonic stage.
However, Chairman Nair had made it clear that for the time
being a manned mission to the moon is not on ISRO’s radar. He pointed out that
a project for launching a manned flight to the moon would be taken up only if it
was fully justified. Adding that for such a challenging mission ISRO would need
to develop many new and novel technologies including a gigantic space booster.
Interestingly, China has hinted that it is working
towards sending a manned mission to the moon by 2020. As such, ISRO could be
under pressure to pursue a project for a manned mission to the earths nearest
celestial neighbor.
Of course, India’s
plan for sending a manned vehicle near the earth’s orbit by 2015 is slowly
assuming a concrete shape. Nair asserted that efforts were on to put in place
facilities to realize the manned flight dream.
As part of the manned mission, ISRO in tie-up with the
Bangalore-based Institute
of Aviation Medicine,
under the Indian Air Force is working towards setting up an advanced training
facility to help future Indian astronauts withstand the rigors of space flight.
This facility will come up on over 100 acres land on Bangalore’s outskirts.
To complement this, a crew management facility is also to be
set-up at the Satish Dhawan Space Centre (SDSC) in Sriharikota
Island on India’s eastern coast. “This will
be the last-minute training facility for astronauts,” said SDSC’s Director MC Dathan.
On another front, also on the anvil is a third launch pad at
SDSC to support the manned mission. Currently, the SDSC has two launch pads.
The Chandrayaaan-1 was launched from the second launch pad of SDSC.
While ISRO has several technologies already available for
the manned mission, there would be need to develop many innovative technologies
to ensure fool-proof life support system, safety, reliability and an escape
system for the crew.
According to the Indian Space Department’s latest Annual
Report the manned mission aimed to build and demonstrate the capability for
carrying humans to a low earth orbit and their safe return to earth. The programme
now envisages developing a fully autonomous orbital vehicle carrying two or
three crew members around the 400km earth orbit and their safe return to earth.
--- INFA
(Copyright India News & Feature Alliance)
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Stem Cell Research:BOON FOR DISEASE CURE, by RK Rao, 14 November 2008, |
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HEALTH SPECIAL
New
Delhi, 14 November 2008
Stem Cell Research
BOON FOR DISEASE CURE
By Radhakrishna Rao
The election of Barack Obama as the American
President holds out hope of clearing the hurdles in the way of stem cell
research which has the potential to evolve innovative treatment strategies for
many of the hitherto incurable diseases afflicting humanity.
For the much-despised Bush Administration,
out to please the fanatical Christian fundamentalist groups in the USA, had put roadblocks
in the way of the highly beneficial stem cell research. His autocratic decision
to provide federal funding only to stem cell lines created from the human
embryo before August 2001 was a reflection of his right-wing ideology steeped
in obscurantist religious beliefs.
Certainly, morality and ethics had
little to do with Bush’s decision on stem cell research. However, with a down-to-earth
Obama in the White House, stem cell researchers are hoping for better and
brighter days ahead. For Obama has made his commitment to remove obstacles in
the way of stem cell research which
holds the hope of alleviating human suffering.
Meanwhile, American researchers have
zeroed in on a new group of stem cells capable of differentiating into heart
muscle known as cardiomyocytes. These stem cells located in the outermost layer
of the heart have the potential to play a crucial role in regenerating injured
heart tissues. “In heart failure, you lose cardiomyocytes. So the only way to
reverse heart failure is to make more of these cells,” says a researcher at
Children’s Hospital in Boston
who is also a pediatric cardiologist
On another front, a US-based bio-technology
company has evolved a novel technique to create stem cell lines without
destroying the human embryos. This path-breaking development, claims the
company could be an effective solution to the controversy over the ethical and
moral issues involved in various aspects of stem cell research. “This will make
it far more difficult to oppose the ongoing stem cell research” asserted a
researcher of the Advanced Cell Technology based in California.
Besides, the company revealed that it
had been successful in turning the clock back on skin cells and transforming
them into stem cells, the building blocks of human tissues and organs. It
elatedly observed that this is the Holy Grail ---- to be able to take a few
skin cells from a patient’s cheek and turn them into stem cells in the
laboratory.
Interestingly, the use of the skin will
ultimately allow doctors and medical researchers to create stem cells with a
specific patient’s genetic code. Indeed, this technique would eventually
obviate the risk of the body rejecting transplanted tissue or organs.
Further, it could also result in the
easy and abundant availability of research material used to test new drugs and
understand the dynamics of diseases and disorders like cancer and diabetes. Moreover,
stem cells are not only capable of
replicating endlessly but also get transformed into one of the more than 200
cell types found in the human body.
In India, the Hyderabad-based LV Prasad
Eye Institute has pioneered an innovative stem cell therapy for treating visual
disorders. This unique treatment regimen involves extracting a piece of limbal
tissue from the healthy eye of the patient and grafting it into the diseased
eye. Significantly, the Institute has over 400 limbal stem cell transplant
surgeries to its credit, a world record. “Even after so many cases, we consider
the process as an extended treatment,” stated a medical researcher at the
institute.
On its part, the New Delhi-based All
India Institute of Medical Sciences (AIIMS) has successfully used stem cell
lines for treating damaged heart muscles of those affected by one of the many
cardiac disorders. In Bangalore’s Manipal Hospital stem cell treatment has been
tried to set right spinal cord injuries with some degree of success. The Chennai-based
Lifeline Institute of Stem Cell Therapy and Research too has reported success
in treating spinal cord injuries with stem cell treatment.
All said and done, putting stem cell
therapy to large scale use would need further trials and fine-tuning of the
procedures. Specially, as in most cases
researchers prefer what is called an autologus mode where stem cells are taken
from the patient themselves with a view to avoid rejection involved in
transplantation procedures.
In addition, the concept of stem
cell banking is catching on in India,
wherein the stem cells of a new born child are stored for possible future use.
The Chennai-based Life Cell is a pioneer in the umbilical cord blood stem cell
banking. Pointed out its Director, “Cord blood stem cells can be used to treat
more than 70 diseases. The research is at a point where if we can include
diabetes and heart diseases also where the chance of them being used could be
as high as one in one hundred.”
Given that the stem cells, described
as the versatile building blocks of the human body, remain undifferentiated in
the embryonic stage. However, they later develop and evolve into specialized
tissues that go on to form the blood, bone and muscles. Because they are
endowed with a tremendous potential to replicate themselves, stem cells are
considered ideal for fixing various disorders in a patient.
In distinct contrast to the
situation in US, Britain
continues to encourage research into the human embryonic stem cell under a
tightly regulated environment. The latest instance of this is the permission
granted for using animal eggs to produce hybrid embryos.
In a major breakthrough, researchers
have been able to demonstrate that mouse embryonic stem cells can be deployed
to predict human breast cancer risk with a high degree of success. In the US researchers
have been able to coax human embryonic stem cells to transform themselves into
three specific heart cell types.
In India, a number of research
institutions including the Tata Institute of Fundamental Research (TIFR) and the
Centre for Cellular and Molecular Biology are active in stem cell research and
its application in health care. Sources in the New Delhi-based Indian Council
of Medical Research (ICMR) pointed out that stem cell research and its clinical
applications would be promoted in the country in view of its tremendous
potential in modern therapeutic and bio-medical research.--- INFA
(Copyright,
India News and Feature Alliance)
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